Malaria models

This project consists of two sub-projects. Modeling the ion homeostasis of asexual blood stage Plasmodium falciparum and modeling the influence of parasite encoded enzymes on lipid metabolism.

The malaria life cycle

In general

Focus on the intraerythrocytic life cycle

Lipid Metabolism

Of a red blood cell (RBC)

Of Plasmodium falciparum

Ion regulation

uRBC

iRBC

Plasmodial ion pumps

Modeling

Ion homeostatis

Volume definition

NPP expression

Non-linear thermodynamic model

Transporter based model